Agressive central giant cell granuloma of the mandible: case report

Authors

  • Ana Reis Durão Department of Dental Radiology – Faculty of Dental Medicine – University of Porto – Portugal.
  • José Teixeira Koch Department of Dental Radiology – Faculty of Dental Medicine – University of Porto – Portugal.
  • Marcelo Miranda Department of Dental Radiology – Faculty of Dental Medicine – University of Porto – Portugal.
  • Aline Morosolli Aline Department of Surgery – Dentistry School – Pontifical Catholic University of Rio Grande do Sul – Porto Alegre – Rio Grande do Sul – Brazil.

DOI:

https://doi.org/10.14295/bds.2015.v18i3.1098

Abstract

Central giant cell granulomas (CGCG) are benign intraosseous proliferative lesions. Usually located are at the anterior region of the maxilla or mandible, although are more frequently found in the mandible. Etiopathogenesis of these lesions has remained unknown, however, some consider them as reparative response rather than neoplastic condition. Clinically CGCG present as asymptomatic, with expansive swelling causing deviation or proliferation of cortical bone. This condition is usually unifocal. Surgical removal is often the preferred treatment. Although nonsurgical treatment methods, such as intralesional corticosteroid injections, systemic calcitonin and interferon have been reported. This article describes the radiographic features of a large CGCG in the anterior mandibular region seen in a 9 year-old patient. Treatment of this lesion included resection of the anterior region of the mandible and replacement by tibia with bone growth factors.

 

Keywords: Central giant cell granuloma; reparative granulomas; mandible; jaws.

 

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Author Biographies

Ana Reis Durão, Department of Dental Radiology – Faculty of Dental Medicine – University of Porto – Portugal.

Department of Dental Radiology

José Teixeira Koch, Department of Dental Radiology – Faculty of Dental Medicine – University of Porto – Portugal.

Department of Dental Radiology

Marcelo Miranda, Department of Dental Radiology – Faculty of Dental Medicine – University of Porto – Portugal.

Department of Dental Radiology

Aline Morosolli Aline, Department of Surgery – Dentistry School – Pontifical Catholic University of Rio Grande do Sul – Porto Alegre – Rio Grande do Sul – Brazil.

Department of Surgery

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Published

2015-09-21

How to Cite

1.
Durão AR, Koch JT, Miranda M, Aline AM. Agressive central giant cell granuloma of the mandible: case report. BDS [Internet]. 2015 Sep. 21 [cited 2025 Aug. 20];18(3):114-8. Available from: https://bds.ict.unesp.br/index.php/cob/article/view/1098

Issue

Vol. 18 No. 3 (2015): Jul. - Sep. / 2015 - Published September 2015

Section

Case Report or Clinical Technique

License

Brazilian Dental Science uses the Creative Commons (CC-BY 4.0) license, thus preserving the integrity of articles in an open access environment. The journal allows the author to retain publishing rights without restrictions.

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