Synthesis and morphological characterization of Polycaprolactone (PCL) membranes with tara extract (Caesalpinia spinosa)

Authors

  • Jhenifer Rodrigues Silva São Paulo State University (Unesp) – Institute of Science and Technology – São José dos Campos – SP - Brazil. http://orcid.org/0000-0002-9028-9586
  • Tabata Prado Sato São Paulo State University (Unesp) – Institute of Science and Technology – São José dos Campos – Department of Dental Materials and Prosthodontics – SP – Brazil. http://orcid.org/0000-0001-6472-8840
  • Alexandre Luiz Souto Borges São Paulo State University (Unesp) – Institute of Science and Technology – São José dos Campos – Department of Dental Materials and Prosthodontics – SP – Brazil. http://orcid.org/0000-0002-5707-7565

DOI:

https://doi.org/10.14295/bds.2019.v22i2.1688

Abstract

Objective: This study aimed the synthesis and morphological characterization of PCL electrospun fibers containing tara extract. Material and Methods: For this, tara extract synthesis was performed by two different extraction methods: rotary evaporator and extractor soxhlet. Then, two solutions were prepared by dissolving 3g of PCL in 2mL of Acetone. The first solution used 0.4 mL tara extract obtained by RE and the second solution used 0.4 mL tara extract obtained by SE. After the solutions electrospinning, under different parameters, obtaining It was obtained the experimental groups: ChTa 1 nanofibers with RE extract, under 12 Kv; ChTa 2 nanofibers with RE extract, under 15 Kv; ChTa 3 nanofibers with ES extract, under 12Kv and ChTa 4 nanofibers with ES extract, under 15kV. Scanning electron micrographs were performed for morphological analysis. Results: Fiber formation was observed for all parameters. About the fiber diameter: ChTa 1 presented a mean of 0.82 ± 0.36?m, ChTa 2 1.232 ±0471?m, ChTa 3 1.469 ± 0.614?m and ChTa 4 1.017 ± 0.417. Also the beads formation was analyzed: ChTa 1 group presented 8 beads, ChTa 2 presented 5, ChTa 3 presented 30 and ChTa 4 presented 15 beads. Conclusion: It can be concluded that it is possible to obtain an effective synthesis of electrospun membranes of PCL and Caesalpinia spinosa extract, indicating a potential of therapeutic application for lesions such as prosthetic stomatitis.

Keywords

Candidiasis; Nanofibers; Tannins.

Downloads

Published

2019-04-30

Issue

Vol. 22 No. 2 (2019): Apr. - Jun. / 2019 - Published April 2019

Section

Clinical or Laboratorial Research

License

COPYRIGHT TRANSFER AND RESPONSIBILITY STATEMENT
 (PDF | Word)

All manuscript's copyright ownership of the article "____________________________________________________________________" is transferred from the author(s) to the BRAZILIAN DENTAL SCIENCE, in the event the work is published. The manuscript has not been published elsewhere and that it has not been submitted simultaneously for publication elsewhere.

We hereby attest the study is original and does not present manipulated data, fraud or plagiarism. We made significant scientific contribution to the study and we are aware of the presented data and in agreement with the final version of the manuscript. We assume complete responsibility for the ethical aspects of the study.

 

This text must be printed and signed by all authors. The scanned version should be submitted as supplemental file during the submission process.