Silver nanoparticles in mouthwashes against infection caused by SARS-CoV-2: a scoping review

Authors

  • Kelly Fernanda Molena Pós Graduanda do Programa de Odontopediatria, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil https://orcid.org/0000-0002-7290-8451
  • Camila Raíssa Oliveira Gontijo Martins Pós Graduanda do Programa de Odontopediatria, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil https://orcid.org/0000-0001-7006-469X
  • Carolina Alves Freiria de Oliveira Pós Graduanda do Programa de Reabilitação Oral Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil. https://orcid.org/0000-0001-7317-3429
  • Murilo Fernando Neuppmann Feres Departamento de Clínica Infantil, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil https://orcid.org/0000-0002-7185-544X
  • Alexandra Mussolino de Queiroz Departamento de Clínica Infantil, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil https://orcid.org/0000-0003-2900-5000

DOI:

https://doi.org/10.4322/bds.2023.e3721

Abstract

The Silver nanoparticle (AgNPs) have received attention for their antiviral potential against SARS-CoV-2. The objective is to conduct a scope review and map the scientific evidence on the use of AgNPs in mouthwashes as an adjunct in decreasing the viral load in the oral cavity of patients with SARS-CoV-2. A search was performed in the PubMed, Medline, Scielo databases, and a manual search in the reference lists, following the standards of the Joanna Briggs Institute for Scoping Review without restriction of year, language or sample size. Thus, 14 articles were included, where they researched the use of AgNPs with antiviral effect against SARS-CoV-2, mouthwashes for SARS-CoV-2 and AgNPs as mouthwashes. We can suggest that AgNPs are likely antiviral therapies for SARS-CoV-2 and its use in mouthwashes associated with other therapies are promising strands for decreasing viral load and infection by the virus.

KEYWORDS

Nanoparticles; Silver; Mouthwashes; COVID-19; SARS-CoV-2.

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Published

2023-06-21

Issue

Vol. 26 No. 2 (2023): Apr - Jun / 2023 - Published Mar 2023

Section

Literature Review