Langerhans cell histiocytosis (histiocytosis x) – in the mandible

Authors

  • Angela Jordão Camargo São Paulo University
  • Mayara Cheade Departament of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil
  • Celso Martinelli Departament of Morphology, Stomatology and Physiology, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil
  • Solange Aparecida Caldeira Monteiro São Paulo University
  • Christiano de Oliveira Santos São Paulo University
  • Plauto Christopher Aranha Watanabe São Paulo University

DOI:

https://doi.org/10.14295/bds.2013.v16i4.898

Abstract

This article reports a case of 65 year-old man consultedin a private radiology dental clinic for a panoramicradiography, where was indicated a radiolucent area,extending into the periapical region of the teeth 35 to 43 to the base of the mandible. Radiographydiagnosis was difficult. The immunohistochemical examination showed immunoreactivity for theproteins CD 68, S-100 and CD 1a. Histopathologicaldiagnosis was obtained for Langerhans cell granuloma(histiocytosis X). Langerhans cell histiocytosis iscaused by the abnormal proliferation of histiocytes, previously called Histiocytosis X. It is a rare diseasethat preferentially affects children and young adultswith a predilection for males and can affect differentparts of the body.

Keywords
Adult; Histiocytosis; Langerhans; Mandible.

Author Biographies

Angela Jordão Camargo, São Paulo University

Departament of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil

Mayara Cheade, Departament of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil

Departament of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, SP, Brazil

Solange Aparecida Caldeira Monteiro, São Paulo University

Departament of Morphology, Stomatology and Physiology, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil

Christiano de Oliveira Santos, São Paulo University

Departament of Morphology, Stomatology and Physiology, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil

Plauto Christopher Aranha Watanabe, São Paulo University

Departament of Morphology, Stomatology and Physiology, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil

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Published

2013-10-02

Issue

Vol. 16 No. 4 (2013): Oct. - Dec. / 2013 - Published December 2013

Section

Case Report or Clinical Technique