Osteoradionecrosis: Case report

Authors

  • Rosana Ferreira Silva Department of Bioscience and Oral Diagnosis – School of Dentistry – Institute of Science and Technology – UNESP – Univ Estadual Paulista – São José dos Campos – SP – Brazil.
  • Zulene Eveline Abreu Ribeiro Private Clinic
  • Lúcio Murilo dos Santos Department of Bioscience and Oral Diagnosis – School of Dentistry – Institute of Science and Technology – UNESP – Univ Estadual Paulista – São José dos Campos – SP – Brazil.
  • Rodrigo Dias Nascimento Department of Diagnosis and Surgery – School of Dentistry – Institute of Science and Technology – UNESP – Univ Estadual Paulista – São José dos Campos – SP – Brazil.
  • Michelli Bianchi de Moraes Department of Diagnosis and Surgery – School of Dentistry – Institute of Science and Technology – UNESP – Univ Estadual Paulista – São José dos Campos – SP – Brazil.
  • Fernando Vagner Raldi Department of Diagnosis and Surgery – School of Dentistry – Institute of Science and Technology – UNESP – Univ Estadual Paulista – São José dos Campos – SP – Brazil.

DOI:

https://doi.org/10.14295/bds.2015.v18i2.1009

Abstract

Patients undergoing radiotherapy alone or as part of the treatment of head and neck cancer are likely to develop osteoradionecrosis (ORN). Dental extractions have been inferred as the main triggering factor of ORN, particularly in mandibular molars. The osteoradionecrosis has been reported in up to 20% of irradiated patients undergoing dental extraction and is recognized as the most severe complication of radiotherapy in the mandible, causing great discomfort and loss of quality of life of patients. The risk of ORN development is related to the dose, technique, and volume of irradiated tissue, and other predisposing factors such as: extraction at peri-radiotherapy period, site of extraction, pre-existing periodontal disease, general trauma, poor oral hygiene, nutritional deficiency, alcohol and smoking, and systemic diseases. The cellular injury and hypoxia caused by decreased blood supply reduce the recoverability of soft tissue and bone, predisposing them to necrosis and osteonecrosis, even spontaneous. Clinical management of osteoradionecrosis is complex and depending on the degree of involvement, it may require analgesics and antibiotics in addition to the adoption of surgical procedures, aiming to eliminate pain, control infection, and prevent or reduce the progression of the lesion. This paper aimed to report a case of osteoradionecrosis treated in the multidisciplinary clinic of the Onco Project - ICT/UNESP (São José dos Campos/SP, Brazil). A female patient aged 65 years with osteoradionecrosis and fistula after radiotherapy of squamous cell carcinoma in gingiva was submitted to tooth extraction, antibiotic therapy and local care with good response and flow interruption through the fistula. During the treatment, the carcinoma relapsed and the patient was referred for oncologic treatment.

 

Downloads

Download data is not yet available.

Downloads

Published

2015-05-19

How to Cite

1.
Silva RF, Ribeiro ZEA, dos Santos LM, Nascimento RD, de Moraes MB, Raldi FV. Osteoradionecrosis: Case report. BDS [Internet]. 2015 May 19 [cited 2025 Aug. 21];18(2):109-14. Available from: https://bds.ict.unesp.br/index.php/cob/article/view/1009

Issue

Vol. 18 No. 2 (2015): Apr. - Jun. / 2015 - Published May 2015

Section

Case Report or Clinical Technique

License

Brazilian Dental Science uses the Creative Commons (CC-BY 4.0) license, thus preserving the integrity of articles in an open access environment. The journal allows the author to retain publishing rights without restrictions.

=================

COPYRIGHT TRANSFER AND RESPONSIBILITY STATEMENT
 (PDF)

For all articles published in the BDS journal, copyright is retained by the authors. Articles are licensed under an open-access Creative Commons CC BY 4.0 license, meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted, provided that the original published version is cited. These conditions allow for maximum use and exposure of the work while ensuring that the authors receive proper credit. All metadata associated with published articles is released under the Creative Commons CC0 Universal Public Domain Dedication.

Before the submission, authors must obtain permission to reproduce any published material (figures, schemes, tables, or any extract of a text) that does not fall into the public domain or for which they do not hold the copyright. Permission should be requested by the authors from the copyright holder (usually the Publisher, please refer to the imprint of the individual publications to identify the copyright holder).

The authors hereby attest that the study is original and does not present manipulated data, fraud, or plagiarism. All names listed made a significant scientific contribution to the study, are aware of the presented data, and agree with the final version of the manuscript. They assume complete responsibility for the ethical aspects of the study.

This text must be printed and signed by all authors. The scanned version should be submitted as supplemental file during the submission process.

Most read articles by the same author(s)

1 2 > >>