Association of chlorhexidine and high fluoride dentifrice on Streptococcus mutans viability using an in vitro biofilm model

Autores

  • Guilherme Bandeira Santana Dentistry Course of Federal University of Piauí
  • Debora Lima Silva Dentistry Course of Federal University of Piauí
  • Josie Haydée Lima Ferreira Microbiology and Parasitology Department, Federal University of Piauí
  • Fabiana Gouveia Rolim Postgraduate Program in Dentistry, Federal University of Piauí
  • Glauber Campos Vale Federal University of Piaui

DOI:

https://doi.org/10.14295/bds.2016.v19i3.1258

Resumo

Objective. This in vitro study investigated the effect of Fluoride (F), Chlorhexidine (CHX), and their association on the viability of Streptococcus mutans using a biofilm model. Materials and Methods. Biofilms were anaerobically grown on glass slides that were vertically suspended in 24-well plates for 5 days.  After 48 h of initial growth, biofilms were treated for the next 72 h, 2x/day with CHX at 0.12% and 2%, F as NaF at 0.08% and 0.4% and their association. Results. CHX treatment decreased the bacteria counts either alone or in association with both F concentrations, when compared with control group and the F treatments alone (p<0.05). Conclusion. No addition effect was observed when CHX and F were used in combination, when compared with CHX used alone.     

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Publicado

2016-09-29

Como Citar

1.
Santana GB, Silva DL, Ferreira JHL, Rolim FG, Vale GC. Association of chlorhexidine and high fluoride dentifrice on Streptococcus mutans viability using an in vitro biofilm model. BDS [Internet]. 29º de setembro de 2016 [citado 12º de setembro de 2025];19(3):9-13. Disponível em: https://bds.ict.unesp.br/index.php/cob/article/view/1258