Is the use of Lactobacillus reuteri probiotic efficient as adjunctive therapy in the treatment of periodontitis? A systematic review

Authors

  • Taina da Silva Tricoly Universidade Estadual Paulista , Instituto de Ciência e Tecnologia, Departamento de Diagnóstico e Cirurgia, São José dos Campos, SP, Brazil. https://orcid.org/0000-0002-4439-8896
  • Camila Lopes Ferreira Universidade Estadual Paulista , Instituto de Ciência e Tecnologia, Departamento de Diagnóstico e Cirurgia, São José dos Campos, SP, Brazil. https://orcid.org/0000-0002-2320-6525
  • Victória Clara da Silva Lima Universidade Estadual Paulista , Instituto de Ciência e Tecnologia, Departamento de Diagnóstico e Cirurgia, São José dos Campos, SP, Brazil. https://orcid.org/0000-0002-7196-3766
  • Andrea Carvalho de Marco Universidade Estadual Paulista , Instituto de Ciência e Tecnologia, Departamento de Diagnóstico e Cirurgia, São José dos Campos, SP, Brazil. https://orcid.org/0000-0002-1894-7855
  • Taciana Marco Ferraz Caneppele Universidade Estadual Paulista , Instituto de Ciência e Tecnologia, Departamento de Diagnóstico e Cirurgia, São José dos Campos, SP, Brazil. https://orcid.org/0000-0003-0521-7922
  • Maria Aparecida Neves Jardini Universidade Estadual Paulista , Instituto de Ciência e Tecnologia, Departamento de Diagnóstico e Cirurgia, São José dos Campos, SP, Brazil. https://orcid.org/0000-0003-3229-8019

DOI:

https://doi.org/10.4322/bds.2023.e3619

Abstract

Objective: This systematic review had the purpose to validate the probiotic Lactobacillus reuteri as adjuvant therapy in the periodontal treatment of periodontitis, by the analysis of randomized controlled trial, controlled clinical trial, and observational studies. Material and Methods: Search keys related to the subject were defined, and the following databases were used as search strategies: MEDLINE via PubMed, Scopus, Web of Science, Cochrane Central Controlled Trials Registry, and EMBASE. The data selection and study were performed by two independent evaluators: first, they selected the article by title and abstract and subsequently qualified according to the bias risk analysis. A narrative synthesis has been performed based on the data obtained from the best-quality articles. After data extraction, their heterogeneity was analyzed, and a meta-analysis was performed. Results: In general, the results of the meta-analysis were positive for the use of probiotics as an adjuvant treatment. Considering the limitations of the comparisons between the analyzed articles studied, the conclusion was that probiotics may provide supplementary benefits to the treatment of periodontitis, with improvement in bleeding on probing rates and probing depth.

KEYWORDS

Lactobacillus reuteri; Periodontal diseases; Periodontitis; Probiotics; Systematic review.

Downloads

Download data is not yet available.

Downloads

Published

2023-02-24

How to Cite

1.
Tricoly T da S, Ferreira CL, Lima VC da S, Marco AC de, Caneppele TMF, Neves Jardini MA. Is the use of Lactobacillus reuteri probiotic efficient as adjunctive therapy in the treatment of periodontitis? A systematic review. BDS [Internet]. 2023 Feb. 24 [cited 2025 Aug. 21];26(1). Available from: https://bds.ict.unesp.br/index.php/cob/article/view/3619

Issue

Vol. 26 No. 1 (2023): Jan - Mar / 2023 - Published Jan 2023

Section

Systematic Review

License

Brazilian Dental Science uses the Creative Commons (CC-BY 4.0) license, thus preserving the integrity of articles in an open access environment. The journal allows the author to retain publishing rights without restrictions.

=================

COPYRIGHT TRANSFER AND RESPONSIBILITY STATEMENT
 (PDF)

For all articles published in the BDS journal, copyright is retained by the authors. Articles are licensed under an open-access Creative Commons CC BY 4.0 license, meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted, provided that the original published version is cited. These conditions allow for maximum use and exposure of the work while ensuring that the authors receive proper credit. All metadata associated with published articles is released under the Creative Commons CC0 Universal Public Domain Dedication.

Before the submission, authors must obtain permission to reproduce any published material (figures, schemes, tables, or any extract of a text) that does not fall into the public domain or for which they do not hold the copyright. Permission should be requested by the authors from the copyright holder (usually the Publisher, please refer to the imprint of the individual publications to identify the copyright holder).

The authors hereby attest that the study is original and does not present manipulated data, fraud, or plagiarism. All names listed made a significant scientific contribution to the study, are aware of the presented data, and agree with the final version of the manuscript. They assume complete responsibility for the ethical aspects of the study.

This text must be printed and signed by all authors. The scanned version should be submitted as supplemental file during the submission process.

Most read articles by the same author(s)

1 2 > >>