Nifedipine-Induced gingival overgrowth

Authors

  • Ornella Florio School of Dentistry of São Jose dos Campos - State University of São Paulo
  • Maysa Tfouni School of Dentistry of São Jose dos Campos - State University of São Paulo
  • Ivan Balducci School of Dentistry of São Jose dos Campos - State University of São Paulo
  • Andrea Carvalho de Marco School of Dentistry of São Jose dos Campos - State University of São Paulo
  • Maria Aparecida Neves Jardini School of Dentistry of São Jose dos Campos - State University of São Paulo
  • Janete Dias Almeida School of Dentistry of São Jose dos Campos - State University of São Paulo

DOI:

https://doi.org/10.14295/bds.2012.v15i4.836

Abstract

Objective: The objective of the present study was to evaluate gingival overgrowth induced by nifedipine and to correlate it with plaque accumulation. Material and Methods: Sixty patients were divided into a treated group (n=30) consisting of hypertensive patients treated with nifedipine and a control group (n=30) consisting of patients without arterial hypertension. The following exams were performed on the first visit: anamnesis, measurement of blood pressure, weight and height, extra- and intraoral examination, and determination of the vertical and horizontal gingival overgrowth indices, plaque index, and bleeding index. The measurements were repeated after 30 days. Results: Most patients using nifedipine (60.7%) presented grade I horizontal gingival overgrowth (1 to 2 mm), with 3.6% showing minimum vertical gingival overgrowth. On the return visit, the plaque index was reduced by 8.3% and bleeding on probing was reduced by 1.5%. A significant difference in the horizontal gingival overgrowth index was observed between the treated and control groups (chi-square test, p = 0.015, p < 0.05). Conclusions: The present results demonstrated moderate gingival overgrowth induced by nifedipine and a correlation with oral hygiene.

Key words: gingival overgrowth, nifedipine, periodontal diseases.

Author Biography

Andrea Carvalho de Marco, School of Dentistry of São Jose dos Campos - State University of São Paulo

Departamento de Diagnóstico e Cirurgia

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Published

2013-03-04

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Section

Clinical or Laboratorial Research Manuscript